Data Mining for Enzymes Search Utility - DME11

Active, Metal and Binding Site Annotations, as well as gene names and domain attributions
are based on Specific Peptides (SPs) extracted from Swissprot Data

Specific Peptide EC Function Location of SP in Protein Predicted Features
NGFGRIGR 1.2.1; With NAD(+) or NADP(+) as acceptor. 9 -
VAINDPF 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 31
Binding Site D=Aspartic acid at location 35 on the protein
Binding site description: NAD (By similarity).

YMVYMFQYDSTHGKF 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 42
Gene: G3P

GKLVING 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 65 -
ITIFQERDP 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 74
Binding Site R=Arginine at location 80 on the protein
Binding site description: NAD; via carbonyl oxygen (By s

IKWGDAGA 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 85 -
ESTGVFT 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 97 -
VIISAPS 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 119 -
ISAPSADAPM 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 121
Binding Site S=Serine at location 122 on the protein
Binding site description: NAD; via carbonyl oxygen.

DAPMFVMGVN 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 127 -
GVNHEKY 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 134 -
SNASCTT 1.2.1; With NAD(+) or NADP(+) as acceptor. 148
Active Site C=Cysteine at location 152 on the protein
Active Site Description: Nucleophile (By similarity).
Binding Site C=Cysteine at location 152 on the protein
Binding site description: Substrate (Potential).

SNASCTTNCLAPL 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 148
Active Site C=Cysteine at location 152 on the protein
Active Site Description: Nucleophile (By similarity).

CTTNCLAP 1.2.1; With NAD(+) or NADP(+) as acceptor. 152
Active Site C=Cysteine at location 152 on the protein
Active Site Description: Nucleophile (By similarity).

LAKVIHD 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 160 -
IVEGLMT 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 170 -
EGLMTTVH 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 172 -
GLMTTVH 1.2.1; With NAD(+) or NADP(+) as acceptor. 173 -
TATQKTV 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 182
Binding Site T=Threonine at location 182 on the protein
Binding site description: Glyceraldehyde 3-phosphate (By

KTVDGPS 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 186 -
WRDGRGA 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 196 -
NIIPASTGAAKAV 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 205 -
TGAAKAVG 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 211 -
AKAVGKV 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 214 -
KAVGKVIP 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 215 -
PELNGKL 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 222 -
LNGKLTG 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 224 -
GKLTGMAFRVP 1.2.1; With NAD(+) or NADP(+) as acceptor. 226
Binding Site R=Arginine at location 234 on the protein
Binding site description: Glyceraldehyde 3-phosphate (By

RVPTANVS 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 234
Binding Site R=Arginine at location 234 on the protein
Binding site description: Glyceraldehyde 3-phosphate (By

NVSVVDLT 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 239 -
VSVVDLT 1.2.1; With NAD(+) or NADP(+) as acceptor. 240 -
AKYDDIK 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 253 -
ASEGPLKG 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 265 -
GPLKGIL 1.2.1; With NAD(+) or NADP(+) as acceptor. 268 -
LKGILGY 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 270 -
AGIALND 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 299 -
LNDHFVKL 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 303 -
FVKLISWYDNE 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 307
Binding Site N=Asparagine at location 316 on the protein
Binding site description: NAD (By similarity).

SWYDNEFGYS 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 312
Binding Site N=Asparagine at location 316 on the protein
Binding site description: NAD (By similarity).

GYSNRVV 1.2.1.12; Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). 319 -

Mapping of the Specific Peptides in the Protein

Red characters denote the location of the Specific Peptide Matches

---------+---------+---------+---------+---------+---------+---------+---------+---------+---------+
MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTG
VFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGR
GALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG
IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE

DME EC Prediction for this protein is: 1.2.1.12
Check another protein

Specific Peptide	EC	Function	Location of SP in Protein	Predicted Features
NGFGRIGR	1.2.1;	With NAD(+) or NADP(+) as acceptor.	9	-
VAINDPF	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	31	Binding Site D=Aspartic acid at location 35 on the protein Binding site description: NAD (By similarity).
YMVYMFQYDSTHGKF	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	42	Gene: G3P
GKLVING	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	65	-
ITIFQERDP	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	74	Binding Site R=Arginine at location 80 on the protein Binding site description: NAD; via carbonyl oxygen (By s
IKWGDAGA	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	85	-
ESTGVFT	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	97	-
VIISAPS	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	119	-
ISAPSADAPM	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	121	Binding Site S=Serine at location 122 on the protein Binding site description: NAD; via carbonyl oxygen.
DAPMFVMGVN	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	127	-
GVNHEKY	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	134	-
SNASCTT	1.2.1;	With NAD(+) or NADP(+) as acceptor.	148	Active Site C=Cysteine at location 152 on the protein Active Site Description: Nucleophile (By similarity). Binding Site C=Cysteine at location 152 on the protein Binding site description: Substrate (Potential).
SNASCTTNCLAPL	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	148	Active Site C=Cysteine at location 152 on the protein Active Site Description: Nucleophile (By similarity).
CTTNCLAP	1.2.1;	With NAD(+) or NADP(+) as acceptor.	152	Active Site C=Cysteine at location 152 on the protein Active Site Description: Nucleophile (By similarity).
LAKVIHD	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	160	-
IVEGLMT	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	170	-
EGLMTTVH	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	172	-
GLMTTVH	1.2.1;	With NAD(+) or NADP(+) as acceptor.	173	-
TATQKTV	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	182	Binding Site T=Threonine at location 182 on the protein Binding site description: Glyceraldehyde 3-phosphate (By
KTVDGPS	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	186	-
WRDGRGA	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	196	-
NIIPASTGAAKAV	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	205	-
TGAAKAVG	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	211	-
AKAVGKV	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	214	-
KAVGKVIP	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	215	-
PELNGKL	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	222	-
LNGKLTG	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	224	-
GKLTGMAFRVP	1.2.1;	With NAD(+) or NADP(+) as acceptor.	226	Binding Site R=Arginine at location 234 on the protein Binding site description: Glyceraldehyde 3-phosphate (By
RVPTANVS	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	234	Binding Site R=Arginine at location 234 on the protein Binding site description: Glyceraldehyde 3-phosphate (By
NVSVVDLT	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	239	-
VSVVDLT	1.2.1;	With NAD(+) or NADP(+) as acceptor.	240	-
AKYDDIK	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	253	-
ASEGPLKG	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	265	-
GPLKGIL	1.2.1;	With NAD(+) or NADP(+) as acceptor.	268	-
LKGILGY	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	270	-
AGIALND	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	299	-
LNDHFVKL	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	303	-
FVKLISWYDNE	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	307	Binding Site N=Asparagine at location 316 on the protein Binding site description: NAD (By similarity).
SWYDNEFGYS	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	312	Binding Site N=Asparagine at location 316 on the protein Binding site description: NAD (By similarity).
GYSNRVV	1.2.1.12;	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).	319	-