Data Mining for Enzymes Search Utility - DME11

Active, Metal and Binding Site Annotations, as well as gene names and domain attributions
are based on Specific Peptides (SPs) extracted from Swissprot Data

Specific Peptide	EC	Function	Location of SP in Protein	Predicted Features
PLQRLRIVRGTQLFED	2.7.10.1;	Receptor protein-tyrosine kinase.	95	Gene: ERBB2
YALAVLDN	2.7.10.1;	Receptor protein-tyrosine kinase.	112	Gene: ERBB2
GLRELQLRSLTEILKGGVLI	2.7.10.1;	Receptor protein-tyrosine kinase.	136	Gene: ERBB2
QCAAGCTGP	2.7.10.1;	Receptor protein-tyrosine kinase.	239	-
TYNTDTFESM	2.7.10.1;	Receptor protein-tyrosine kinase.	273	Gene: ERBB2
CPYNYLST	2.7.10.1;	Receptor protein-tyrosine kinase.	299	Gene: ERBB2
LQVFETLEEITGYLYISAWP	2.7.10.1;	Receptor protein-tyrosine kinase.	397	Gene: ERBB2
FLRGQECV	2.7.10.1;	Receptor protein-tyrosine kinase.	534	Gene: ERBB2
CQPCPINCTHSC	2.7.10.1;	Receptor protein-tyrosine kinase.	623	Gene: ERBB2
GCPAEQRASP	2.7.10.1;	Receptor protein-tyrosine kinase.	641	Gene: ERBB2
ELVEPLTPSG	2.7.10.1;	Receptor protein-tyrosine kinase.	695	-
KETELRK	2.7.10.1;	Receptor protein-tyrosine kinase.	716	-
VKIPVAIK	2.7.10.1;	Receptor protein-tyrosine kinase.	746	Domain: Protein kinase
LDEAYVMA	2.7.10.1;	Receptor protein-tyrosine kinase.	768	Domain: Protein kinase
RLLGICLTS	2.7.10.1;	Receptor protein-tyrosine kinase.	784	Domain: Protein kinase
TQLMPYGCLLD	2.7.10.1;	Receptor protein-tyrosine kinase.	798	Domain: Protein kinase
RGRLGSQDLLNWC	2.7.10.1;	Receptor protein-tyrosine kinase.	814	Domain: Protein kinase Gene: ERBB2
RLVHRDLAARNVLVKSPNHVKITDFGLARLL	2.7.10.1;	Receptor protein-tyrosine kinase.	840	Active Site D=Aspartic acid at location 845 on the protein Active Site Description: Proton acceptor (By similarity Domain: Protein kinase
RDLAARN	2.7.10;	Protein-tyrosine kinases.	844	Active Site D=Aspartic acid at location 845 on the protein Active Site Description: Proton acceptor (By similarity Domain: Protein kinase
AARNVLV	2.7.10;	Protein-tyrosine kinases.	847	Domain: Protein kinase
GGKVPIKW	2.7.10.1;	Receptor protein-tyrosine kinase.	881	Domain: Protein kinase
SDVWSYGVT	2.7.10;	Protein-tyrosine kinases.	903	Domain: Protein kinase
YGVTVWE	2.7.10.1;	Receptor protein-tyrosine kinase.	908	Domain: Protein kinase
KPYDGIP	2.7.10.1;	Receptor protein-tyrosine kinase.	921	Domain: Protein kinase
GERLPQP	2.7.10;	Protein-tyrosine kinases.	938	Domain: Protein kinase
GERLPQPPICTI	2.7.10.1;	Receptor protein-tyrosine kinase.	938	Domain: Protein kinase
MVKCWMID	2.7.10.1;	Receptor protein-tyrosine kinase.	955	Domain: Protein kinase
RPRFRELV	2.7.10.1;	Receptor protein-tyrosine kinase.	966	Domain: Protein kinase
MARDPQR	2.7.10.1;	Receptor protein-tyrosine kinase.	979	Domain: Protein kinase
DSTFYRSLLEDDDMG	2.7.10.1;	Receptor protein-tyrosine kinase.	1001	Gene: ERBB2
LVDAEEYLVPQQGFF	2.7.10.1;	Receptor protein-tyrosine kinase.	1017	Gene: ERBB2
SPLQRYSEDPT	2.7.10.1;	Receptor protein-tyrosine kinase.	1107	Gene: ERBB2
ETDGYVAPL	2.7.10.1;	Receptor protein-tyrosine kinase.	1123	Gene: ERBB2
RPAGATLERPKTLSP	2.7.10.1;	Receptor protein-tyrosine kinase.	1161	Gene: ERBB2
AENPEYL	2.7.10.1;	Receptor protein-tyrosine kinase.	1243	-

Mapping of the Specific Peptides in the Protein

Red characters denote the location of the Specific Peptide Matches


---------+---------+---------+---------+---------+---------+---------+---------+---------+---------+
MELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLR
IVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCK
GSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVF
ETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRP
EDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARC
PSGVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPL
TPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQL
MPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPL
DSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQS
LPTHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQ
GGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV


DME EC Prediction for this protein is: 2.7.10.1
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