Data Mining for Enzymes Search Utility - DME11

Active, Metal and Binding Site Annotations, as well as gene names and domain attributions
are based on Specific Peptides (SPs) extracted from Swissprot Data

Specific Peptide	EC	Function	Location of SP in Protein	Predicted Features
DQSFPGF	3.1.1.8;	Cholinesterase.	98	Gene: CHLE
GSEMWNPN	3.1.1;	Carboxylic ester hydrolases.	106	-
LSEDCLYLNVW	3.1.1;	Carboxylic ester hydrolases.	116	-
PKPKNATV	3.1.1.8;	Cholinesterase.	130	Gene: CHLE
WIYGGGF	3.1.1;	Carboxylic ester hydrolases.	140	-
FQTGTSSL	3.1.1.8;	Cholinesterase.	146	Gene: CHLE
VYDGKFL	3.1.1.8;	Cholinesterase.	155	Gene: CHLE
VSMNYRVG	3.1.1;	Carboxylic ester hydrolases.	170	-
NYRVGALGFLALPGNPEAPGN	3.1.1.8;	Cholinesterase.	173	Gene: CHLE
GFLALPG	3.1.1;	Carboxylic ester hydrolases.	180	-
LALQWVQ	3.1.1;	Carboxylic ester hydrolases.	201	-
NIAAFGG	3.1.1;	Carboxylic ester hydrolases.	209	-
FGESAGA	3.1.1;	Carboxylic ester hydrolases.	223	Active Site S=Serine at location 226 on the protein Active Site Description: Acyl-ester intermediate (By si
TEIIKCLRNKD	3.1.1.8;	Cholinesterase.	286	Gene: CHLE
NFGPTVDGDFLTDMP	3.1.1.8;	Cholinesterase.	317	Gene: CHLE
QILVGVNKDEGTAFLVYGAPGFSKDN	3.1.1.8;	Cholinesterase.	344	Active Site E=Glutamic acid at location 353 on the protein Active Site Description: Charge relay system (By simila Gene: CHLE
GVNKDEG	3.1.1;	Carboxylic ester hydrolases.	348	Active Site E=Glutamic acid at location 353 on the protein Active Site Description: Charge relay system (By simila
YGAPGFSKD	3.1.1;	Carboxylic ester hydrolases.	360	-
ITRKEFQEGL	3.1.1.8;	Cholinesterase.	373	Gene: CHLE
FPGVSEFG	3.1.1.8;	Cholinesterase.	386	Gene: CHLE
AFFYYFEHRS	3.1.1.8;	Cholinesterase.	444	Gene: CHLE
WPEWMGV	3.1.1;	Carboxylic ester hydrolases.	458	-
HGYEIEF	3.1.1;	Carboxylic ester hydrolases.	466	Active Site H=Histidine at location 466 on the protein Active Site Description: Charge relay system (By simila
QKYLTLN	3.1.1.8;	Cholinesterase.	526	Gene: CHLE
TKLRAQQCRFWT	3.1.1.8;	Cholinesterase.	540	Gene: CHLE
EWKAGFHRW	3.1.1.8;	Cholinesterase.	570	Gene: CHLE
FNDYTSKKE	3.1.1.8;	Cholinesterase.	589	Gene: CHLE

Mapping of the Specific Peptides in the Protein

Red characters denote the location of the Specific Peptide Matches


---------+---------+---------+---------+---------+---------+---------+---------+---------+---------+
MHSKVTIICIRFLFWFLLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQS
FPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQ
LALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEI
LLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFH
YTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWA
NFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKVLEMTGNIDEAEWEWKAGFHRWNNYMMDWKNQFNDYTSKKESCV
GL


DME EC Prediction for this protein is: 3.1.1.8
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