Data Mining for Enzymes Search Utility - DME11

Active, Metal and Binding Site Annotations, as well as gene names and domain attributions
are based on Specific Peptides (SPs) extracted from Swissprot Data


Specific PeptideECFunctionLocation of SP in ProteinPredicted Features
WAVLVTATL2.7.10.1;Receptor protein-tyrosine kinase. 10
  • Gene: FGFR1
GDLLQLRCRLRDDV2.7.10.1;Receptor protein-tyrosine kinase. 48
  • Domain: Ig-like C2-type
  • Gene: FGFR1
DVQSINW2.7.10.1;Receptor protein-tyrosine kinase. 60
  • Domain: Ig-like C2-type
  • Gene: FGFR1
NRTRITG2.7.10.1;Receptor protein-tyrosine kinase. 77
  • Domain: Ig-like C2-type
  • Gene: FGFR1
DSGLYAC2.7.10.1;Receptor protein-tyrosine kinase. 95
  • Domain: Ig-like C2-type
SVNVSDALPS2.7.10.1;Receptor protein-tyrosine kinase. 115
  • Domain: Ig-like C2-type
  • Gene: FGFR1
DDSSSEEKE2.7.10.1;Receptor protein-tyrosine kinase. 132
  • Gene: FGFR1
PEKMEKKLHAVPAAKTVKF2.7.10.1;Receptor protein-tyrosine kinase. 158
  • Domain: Ig-like C2-type
  • Gene: FGFR1
WLKNGKEF2.7.10.1;Receptor protein-tyrosine kinase. 190
  • Domain: Ig-like C2-type
SVVPSDKG2.7.10.1;Receptor protein-tyrosine kinase. 219
  • Domain: Ig-like C2-type
GSINHTY2.7.10.1;Receptor protein-tyrosine kinase. 237
  • Domain: Ig-like C2-type
LDVVERSPH2.7.10.1;Receptor protein-tyrosine kinase. 245
  • Domain: Ig-like C2-type
ERSPHRPILQAGLP2.7.10.1;Receptor protein-tyrosine kinase. 249 -
PILQAGLPAN2.7.10.1;Receptor protein-tyrosine kinase. 255
  • Domain: Ig-like C2-type
PHIQWLK2.7.10.1;Receptor protein-tyrosine kinase. 285
  • Domain: Ig-like C2-type
QWLKHIEVNGS2.7.10.1;Receptor protein-tyrosine kinase. 288
  • Domain: Ig-like C2-type
NGSKIGPD2.7.10.1;Receptor protein-tyrosine kinase. 296
  • Domain: Ig-like C2-type
LKTAGVNT2.7.10.1;Receptor protein-tyrosine kinase. 311
  • Domain: Ig-like C2-type
AGVNTTD2.7.10.1;Receptor protein-tyrosine kinase. 314
  • Domain: Ig-like C2-type
EDAGEYTCLAGNSIG2.7.10.1;Receptor protein-tyrosine kinase. 334
  • Domain: Ig-like C2-type
SHHSAWL2.7.10.1;Receptor protein-tyrosine kinase. 350
  • Domain: Ig-like C2-type
SAWLTVL2.7.10.1;Receptor protein-tyrosine kinase. 353
  • Domain: Ig-like C2-type
LEIIIYCTGA2.7.10.1;Receptor protein-tyrosine kinase. 375
  • Gene: FGFR1
AVHKLAKS2.7.10.1;Receptor protein-tyrosine kinase. 413 -
PLRRQVTV2.7.10;Protein-tyrosine kinases. 422 -
RRQVTVS2.7.10;Protein-tyrosine kinases. 424 -
RLSSSGTPML2.7.10.1;Receptor protein-tyrosine kinase. 448
  • Gene: FGFR1
SEYELPEDP2.7.10.1;Receptor protein-tyrosine kinase. 461 -
LPEDPRWE2.7.10.1;Receptor protein-tyrosine kinase. 465 -
LGKPLGEGCFGQV2.7.10.1;Receptor protein-tyrosine kinase. 480
  • Domain: Protein kinase
VAVKMLK2.7.10.1;Receptor protein-tyrosine kinase. 511
  • Binding Site K=Lysine at location 514 on the protein
  • Binding site description: ATP (By similarity).
  • Domain: Protein kinase
EKDLSDL2.7.10.1;Receptor protein-tyrosine kinase. 522
  • Domain: Protein kinase
DLISEME2.7.10.1;Receptor protein-tyrosine kinase. 527
  • Domain: Protein kinase
SEMEMMK2.7.10.1;Receptor protein-tyrosine kinase. 530
  • Domain: Protein kinase
NIINLLG2.7.10.1;Receptor protein-tyrosine kinase. 543
  • Domain: Protein kinase
CTQDGPLY2.7.10.1;Receptor protein-tyrosine kinase. 551
  • Domain: Protein kinase
GPLYVIVE2.7.10.1;Receptor protein-tyrosine kinase. 555
  • Domain: Protein kinase
QVARGME2.7.10.1;Receptor protein-tyrosine kinase. 606
  • Domain: Protein kinase
ARGMEYLAS2.7.10.1;Receptor protein-tyrosine kinase. 608
  • Domain: Protein kinase
CIHRDLAARNVLV2.7.10.1;Receptor protein-tyrosine kinase. 619
  • Active Site D=Aspartic acid at location 623 on the protein
  • Active Site Description: Proton acceptor (By similarity
  • Domain: Protein kinase
RDLAARN2.7.10;Protein-tyrosine kinases. 622
  • Active Site D=Aspartic acid at location 623 on the protein
  • Active Site Description: Proton acceptor (By similarity
  • Domain: Protein kinase
AARNVLV2.7.10;Protein-tyrosine kinases. 625
  • Domain: Protein kinase
VMKIADFGLAR2.7.10.1;Receptor protein-tyrosine kinase. 636
  • Domain: Protein kinase
DFGLARDI2.7.10.1;Receptor protein-tyrosine kinase. 641
  • Domain: Protein kinase
IDYYKKT2.7.10.1;Receptor protein-tyrosine kinase. 651
  • Domain: Protein kinase
LPVKWMA2.7.10.1;Receptor protein-tyrosine kinase. 662
  • Domain: Protein kinase
PVKWMAPE2.7.10.1;Receptor protein-tyrosine kinase. 663
  • Domain: Protein kinase
YTHQSDVWS2.7.10.1;Receptor protein-tyrosine kinase. 677
  • Domain: Protein kinase
WEIFTLGGSP2.7.10.1;Receptor protein-tyrosine kinase. 691
  • Domain: Protein kinase
PVEELFKLLKEGHRMD2.7.10.1;Receptor protein-tyrosine kinase. 705
  • Domain: Protein kinase
EGHRMDKP2.7.10.1;Receptor protein-tyrosine kinase. 715
  • Domain: Protein kinase
NCTNELY2.7.10.1;Receptor protein-tyrosine kinase. 724
  • Domain: Protein kinase
PSQRPTFKQLVE2.7.10.1;Receptor protein-tyrosine kinase. 741
  • Domain: Protein kinase
LVEDLDR2.7.10.1;Receptor protein-tyrosine kinase. 750
  • Domain: Protein kinase

Mapping of the Specific Peptides in the Protein

Red characters denote the location of the Specific Peptide Matches


---------+---------+---------+---------+---------+---------+---------+---------+---------+---------+
MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYA
C
VTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPD
HRIGGYKVRYATWSIIMD
SVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKI
GPD
NLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMK
SGTKKSDFHSQM
AVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGL
DKDKPNRVTK
VAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDL
VSCAY
QVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSP
YPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEP
LPEEPCLPRHPAQLANGGLKRR



DME EC Prediction for this protein is: 2.7.10.1
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