Data Mining for Enzymes Search Utility - DME11

Active, Metal and Binding Site Annotations, as well as gene names and domain attributions
are based on Specific Peptides (SPs) extracted from Swissprot Data

Specific Peptide	EC	Function	Location of SP in Protein	Predicted Features
CYYNHTQ	2.7.10.1;	Receptor protein-tyrosine kinase.	100	Domain: Ig-like C2-type Gene: PGFRA
IYIYVPDP	2.7.10.1;	Receptor protein-tyrosine kinase.	117	Domain: Ig-like C2-type Gene: PGFRA
GETIVVTC	2.7.10.1;	Receptor protein-tyrosine kinase.	228	Domain: Ig-like C2-type Gene: PGFRA
TLIENLTEI	2.7.10.1;	Receptor protein-tyrosine kinase.	355	Domain: Ig-like C2-type Gene: PGFRA
ENLTEITT	2.7.10.1;	Receptor protein-tyrosine kinase.	358	Domain: Ig-like C2-type Gene: PGFRA
LIRAKEEDSG	2.7.10.1;	Receptor protein-tyrosine kinase.	381	Domain: Ig-like C2-type Gene: PGFRA
ELTVAAAVLVLLVIVIISLIVLV	2.7.10.1;	Receptor protein-tyrosine kinase.	524	Gene: PGFRA
KPRYEIRW	2.7.10.1;	Receptor protein-tyrosine kinase.	552	-
DGHEYIYVDP	2.7.10.1;	Receptor protein-tyrosine kinase.	568	-
VAVKMLK	2.7.10.1;	Receptor protein-tyrosine kinase.	624	Binding Site K=Lysine at location 627 on the protein Binding site description: ATP (By similarity). Domain: Protein kinase
ALMSELK	2.7.10.1;	Receptor protein-tyrosine kinase.	640	Domain: Protein kinase
NIVNLLGACT	2.7.10.1;	Receptor protein-tyrosine kinase.	656	Domain: Protein kinase
GPIYIITEYC	2.7.10.1;	Receptor protein-tyrosine kinase.	668	Domain: Protein kinase
PIYIITE	2.7.10;	Protein-tyrosine kinases.	669	Domain: Protein kinase
RSYVILS	2.7.10.1;	Receptor protein-tyrosine kinase.	718	Domain: Protein kinase Gene: PGFRA
QYVPMLE	2.7.10.1;	Receptor protein-tyrosine kinase.	741	Domain: Protein kinase Gene: PGFRA
SKYSDIQRS	2.7.10.1;	Receptor protein-tyrosine kinase.	752	Domain: Protein kinase Gene: PGFRA
DLLSFTYQVA	2.7.10.1;	Receptor protein-tyrosine kinase.	794	Domain: Protein kinase Gene: PGFRA
QVARGME	2.7.10.1;	Receptor protein-tyrosine kinase.	801	Domain: Protein kinase
FLASKNCVHRDLAARNVL	2.7.10.1;	Receptor protein-tyrosine kinase.	808	Active Site D=Aspartic acid at location 818 on the protein Active Site Description: Proton acceptor (By similarity Domain: Protein kinase
RDLAARN	2.7.10;	Protein-tyrosine kinases.	817	Active Site D=Aspartic acid at location 818 on the protein Active Site Description: Proton acceptor (By similarity Domain: Protein kinase
AARNVLL	2.7.10;	Protein-tyrosine kinases.	820	Domain: Protein kinase
KICDFGLARD	2.7.10.1;	Receptor protein-tyrosine kinase.	833	Domain: Protein kinase
DFGLARDI	2.7.10.1;	Receptor protein-tyrosine kinase.	836	Domain: Protein kinase
LPVKWMA	2.7.10.1;	Receptor protein-tyrosine kinase.	857	Domain: Protein kinase
PVKWMAPE	2.7.10.1;	Receptor protein-tyrosine kinase.	858	Domain: Protein kinase
KWMAPESIF	2.7.10.1;	Receptor protein-tyrosine kinase.	860	Domain: Protein kinase
LYTTLSDVWS	2.7.10.1;	Receptor protein-tyrosine kinase.	871	Domain: Protein kinase
SDVWSYGI	2.7.10;	Protein-tyrosine kinases.	876	Domain: Protein kinase
GILLWEIF	2.7.10.1;	Receptor protein-tyrosine kinase.	882	Domain: Protein kinase
WEIFSLG	2.7.10.1;	Receptor protein-tyrosine kinase.	886	Domain: Protein kinase
LGGTPYP	2.7.10.1;	Receptor protein-tyrosine kinase.	891	Domain: Protein kinase
FYNKIKSGYRM	2.7.10.1;	Receptor protein-tyrosine kinase.	905	Domain: Protein kinase Gene: PGFRA
EPEKRPSFYHLSEIVE	2.7.10.1;	Receptor protein-tyrosine kinase.	936	Domain: Protein kinase Gene: PGFRA
FLKSDHPAV	2.7.10.1;	Receptor protein-tyrosine kinase.	969	-
YIGVTYKNE	2.7.10.1;	Receptor protein-tyrosine kinase.	988	Gene: PGFRA
DEQRLSADSGYI	2.7.10.1;	Receptor protein-tyrosine kinase.	1008	Gene: PGFRA
PLPDIDPV	2.7.10.1;	Receptor protein-tyrosine kinase.	1021	Gene: PGFRA
KRNRHSSQTSEESAI	2.7.10.1;	Receptor protein-tyrosine kinase.	1036	Gene: PGFRA

Mapping of the Specific Peptides in the Protein

Red characters denote the location of the Specific Peptide Matches


---------+---------+---------+---------+---------+---------+---------+---------+---------+---------+
MGTSHPAFLVLGCLLTGLSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYPMSEEESSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTC
YYNHTQTEENELEGRHIYIYVPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLHNSEGVVPASYDSRQGFNGTFTVGPYICEATVKGKKFQT
IPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNNEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATREVK
EMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVRAYPPPRISWLKNNLTLIENLTEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVAQNED
AVKSYTFELLTQVPSSILDLVDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTILANNVSNIITEIHSRDRSTVEGRVTFAKVEETIAVR
CLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVIISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSHHPEK
PKKELDIFGLNPADESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLLSDDNSEGLTLLDLLSFTY
QVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKL
KDWEGGLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL


DME EC Prediction for this protein is: 2.7.10.1
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